Peptide Database

Peptide NameBeta-insect excitatory toxin BmKIT1

Function Ontology

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC333H523N83O106S8

DescriptionStandard

        KKNGYAVDSSGKVSECLLNNYCNNICTKVYYATSGYCCLLSCYCFGLDDDKAVLKIKDATKSYCDVQII
    

Molecular Weight7641.73 Da

Isoelectric Point (pI)7.66

Net Charge (pH 7.0)0.68

Net Charge (pH 7.4) 0.33

Charge Density (pH 7.0) 0.0098

GRAVY Index-0.04

Hydrophobic Moment 0.58

Boman Index0.04

Instability Index40.92

Aliphatic Index 83.33

Aromaticity 0.1159

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10930.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3093.60

LogP -32.49

H-bond Donors 115.0

H-bond Acceptors 115.0

Rotatable Bonds 255.0

Heavy Atoms 530.0

Ring Count 8.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346801 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilySodium channel inhibitor family

Tax ID34649; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide16-37; 22-42; 26-44; 38-64

Bio-Activity Profile

Function

Toxin Venom Sodium channel inhibitor family Ion channel inhibitor Host defense