Peptide Database

Peptide NameHalocyntin

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC126H190N38O31

DescriptionStandard

        FWGHIWNAVKRVGANALHGAVTGALS
    

Molecular Weight2733.09 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)1.93

Net Charge (pH 7.4) 1.63

Charge Density (pH 7.0) 0.0744

GRAVY Index0.38

Hydrophobic Moment 0.67

Boman Index0.31

Instability Index15.12

Aliphatic Index 97.69

Aromaticity 0.1154

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1094.32

LogP -9.61

H-bond Donors 39.0

H-bond Acceptors 35.0

Rotatable Bonds 84.0

Heavy Atoms 195.0

Ring Count 7.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0423562 VERIFIED: YES

Provenance & Taxonomy

OrganismHalocynthia papillosa [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetGram-positive bacteria (Native, Synthetic): Micrococcus luteus A270

Activity0.39-0.78 μM

MethodMBC

RECORD: Rec_0426618 VERIFIED: YES