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MYP_055655
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Basic Information
Halocyntin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
26 amino acids
C126H190N38O31
Standard
Sequence
FWGHIWNAVKRVGANALHGAVTGALS
Physicochemical Analysis
2733.09 Da
11.00
1.93
1.63
0.0744
0.38
0.67
0.31
15.12
97.69
0.1154
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1094.32
-9.61
39.0
35.0
84.0
195.0
7.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0225991 VERIFIED: YES
Provenance & Taxonomy
Halocynthia papillosa [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
Escherichia coli
PMID19085906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19085906/
RECORD: Rec_0227549 VERIFIED: YES
Provenance & Taxonomy
Halocynthia papillosa [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa 100720 T
100 μM
MBC
PaperPubMed PMID: 19085906 PMID19085906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19085906/
RECORD: Rec_0233994 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0236669 VERIFIED: YES
Provenance & Taxonomy
Halocynthia papillosa [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Neisseria gonorrhoeae 103711
25-50 μM
MBC
PaperPubMed PMID: 19085906 PMID19085906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19085906/
RECORD: Rec_0262783 VERIFIED: YES
Provenance & Taxonomy
Halocynthia papillosa [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PaperPubMed PMID: 19085906 PMID19085906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19085906/
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