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MYP_055655
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Basic Information
Halocyntin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
26 amino acids
C126H190N38O31
Standard
Sequence
FWGHIWNAVKRVGANALHGAVTGALS
Physicochemical Analysis
2733.09 Da
11.00
1.93
1.63
0.0744
0.38
0.67
0.31
15.12
97.69
0.1154
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1094.32
-9.61
39.0
35.0
84.0
195.0
7.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0187082 VERIFIED: YES
Provenance & Taxonomy
Halocynthia papillosa [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
Salmonella Typhimurium
PMID19085906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19085906/
RECORD: Rec_0200830 VERIFIED: YES
Provenance & Taxonomy
Halocynthia papillosa [Animal]
Halocyntin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperJ Pept Sci. 2009 Jan;15(1):48-55 | http://www.ncbi.nlm.nih.gov/pubmed/19085906 PMID19085906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19085906/
RECORD: Rec_0205297 VERIFIED: YES
Provenance & Taxonomy
Halocynthia papillosa [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
12.5-25 μM
MBC
PaperPubMed PMID: 19085906 PMID19085906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19085906/
RECORD: Rec_0218165 VERIFIED: YES
Provenance & Taxonomy
Halocynthia papillosa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
A. viridans
3.1-6.2 μM
MBC
PaperHalocyntin and papillosin, two new antimicrobial peptides isolated from hemocytes of the solitary tunicate, Halocynthia papillosa.
RECORD: Rec_0224030 VERIFIED: YES
Provenance & Taxonomy
Halocynthia papillosa [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
Micrococcus luteus
PMID19085906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19085906/
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