Peptide Database

Peptide NameDefensin-A2 (DefA2) (OaDefA2)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length97 amino acids

Chemical FormulaC447H748N126O154S10

DescriptionStandard

        MRTLSLLLALLFLAAQTLAQPIDEGAEEVITEEPEITETQDPTTIMLIERGIGGDSTDATRSTITCYCRSRCRMLEKNSGTCRSSNCTYTLCCKKTS
    

Molecular Weight10672.12 Da

Isoelectric Point (pI)4.88

Net Charge (pH 7.0)-3.54

Net Charge (pH 7.4) -3.89

Charge Density (pH 7.0) -0.0365

GRAVY Index-0.19

Hydrophobic Moment 0.55

Boman Index-0.04

Instability Index52.81

Aliphatic Index 81.55

Aromaticity 0.0309

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4548.01

LogP -55.76

H-bond Donors 169.0

H-bond Acceptors 161.0

Rotatable Bonds 360.0

Heavy Atoms 737.0

Ring Count 6.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0212228 VERIFIED: YES

Provenance & Taxonomy

OrganismOrnithorhynchus anatinus [Animal]

FamilyAlpha-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic