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MYP_055594
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Basic Information
Beta-purothionin
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
45 amino acids
C203H347N67O59S8
Standard
Sequence
KSCCKSTLGRNCYNLCRARGAQKLCANVCRCKLTSGLSCPKDFPK
Physicochemical Analysis
4926.86 Da
9.54
8.68
8.34
0.1928
-0.40
0.69
-0.23
25.71
56.44
0.0444
1490.00
1990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2081.13
-27.86
82.0
76.0
167.0
337.0
4.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0337222 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
plant thionin (TC 1.C.44) family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-39; 4-31; 12-29; 16-25
Bio-Activity Profile
Toxin Venom plant thionin (TC 1.C.44) family Host defense
PaperPDB 1BHP structural record; X-ray; 1.70 A; chain A; residues 1-45
RECORD: Rec_0337423 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
inoculum 100000,and 2 ug/ml inoculum 1000, S. cerevisiae
8 μg/mL
MIC
PaperInhibition of brewer's yeasts by wheat purothionins.
RECORD: Rec_0345403 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
C. lindemuthianum
15 μg/mL
IC50
PaperInhibition of brewer's yeasts by wheat purothionins.
RECORD: Rec_0378186 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
Thionin
4565
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Yeast Toxin Anti-Gram-negative
Xanthomonas phaseoli
12 μg/mL
MIC
PMID5031563;9909869;10000000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5031563/
RECORD: Rec_0379623 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
Thionin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Xanthomonas phaseoli
12 μg/mL
MIC
PMID5031563 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5031563/
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