Peptide Database

Peptide NameSLAY-screened peptide P812

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC95H134N24O32

DescriptionStandard

        YAHAPYEDDVPPQHGVVTE
    

Molecular Weight2124.22 Da

Isoelectric Point (pI)4.52

Net Charge (pH 7.0)-4.05

Net Charge (pH 7.4) -4.37

Charge Density (pH 7.0) -0.2134

GRAVY Index-0.85

Hydrophobic Moment 0.12

Boman Index0.05

Instability Index64.39

Aliphatic Index 56.32

Aromaticity 0.1053

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 871.09

LogP -7.56

H-bond Donors 27.0

H-bond Acceptors 30.0

Rotatable Bonds 59.0

Heavy Atoms 151.0

Ring Count 7.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0048012 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/