Peptide Database

Peptide NameHR2-44

Function Ontology

Antiviral

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC216H354N58O74

DescriptionStandard

        GDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYI
    

Molecular Weight4947.47 Da

Isoelectric Point (pI)4.33

Net Charge (pH 7.0)-4.23

Net Charge (pH 7.4) -4.45

Charge Density (pH 7.0) -0.0961

GRAVY Index-0.37

Hydrophobic Moment 0.70

Boman Index-0.01

Instability Index35.68

Aliphatic Index 121.82

Aromaticity 0.0455

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2198.85

LogP -21.90

H-bond Donors 72.0

H-bond Acceptors 70.0

Rotatable Bonds 175.0

Heavy Atoms 348.0

Ring Count 2.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056918 VERIFIED: YES

Provenance & Taxonomy

OrganismSevere acute respiratory syndrome-related coronavirus [Virus]

FamilyHR2-derived fusion inhibitor

Tax ID694009

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

TargetSevere acute respiratory syndrome coronavirus

Activity0.5 μM

MethodIC50