Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC436H675N121O134S14

DescriptionStandard

        MKTFWVAVAVAVVLTCICMEESSAVPVTEVPDEEEPMSYDYPLTEHEEPSDDSWVMPYSPRARRHRRKCKFCCNCCSNICQTCCTRRF
    

Molecular Weight10204.66 Da

Isoelectric Point (pI)5.29

Net Charge (pH 7.0)-3.40

Net Charge (pH 7.4) -3.89

Charge Density (pH 7.0) -0.0386

GRAVY Index-0.32

Hydrophobic Moment 0.53

Boman Index-0.08

Instability Index95.87

Aliphatic Index 53.07

Aromaticity 0.0909

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 16095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4071.64

LogP -41.27

H-bond Donors 152.0

H-bond Acceptors 147.0

Rotatable Bonds 322.0

Heavy Atoms 705.0

Ring Count 19.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0005082 VERIFIED: NO

Provenance & Taxonomy

OrganismNotothenia angustata [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0328725 VERIFIED: NO