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MYP_055516
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Basic Information
C14-KLlK
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
5 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XKLLK
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0357156 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
C14, C- terminal NH2 at 1; C14, C- terminal NH2
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Aspergillus fumigatus
6.25 μM
MIC
PMID17038500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17038500/
RECORD: Rec_0362318 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
C12, C- terminal NH2 at 1; C12, C- terminal NH2
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus II 6538P
12.5 μM
MIC
PMID17038500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17038500/
RECORD: Rec_0367055 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
C16, C- terminal NH2 at 1; C16, C- terminal NH2
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa 27853
100 μM
MIC
PMID17038500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17038500/
RECORD: Rec_0384792 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
C12, C- terminal NH2 at 1; C12, C- terminal NH2
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
12.5 μM
MIC
PMID17038500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17038500/
RECORD: Rec_0414620 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
C12, C- terminal NH2 at 1; C12, C- terminal NH2
Bio-Activity Profile
Hemolytic
human RBCs
Hemolysis
PMID17038500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17038500/
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