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MYP_055513
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Basic Information
Colicin-E7 (EC 3.1.-.-)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibiotic activity
Enzyme / Catalytic activity ▸ Hydrolase
Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
576 amino acids
C2664H4259N809O838S10
Standard
Sequence
MSGGDGRGHNSGAHNTGGNINGGPTGLGGNGGASDGSGWSSENNPWGGGSGSGVHWGGGSGHGNGGGNSNSGGGSNSSVAAPMAFGFPALAAPGAGTLGISVSGEALSAAIADIFAALKGPFKFSAWGIALYGILPSEIAKDDPNMMSKIVTSLPAETVTNVQVSTLPLDQATVSVTKRVTDVVKDTRQHIAVVAGVPMSVPVVNAKPTRTPGVFHASFPGVPSLTVSTVKGLPVSTTLPRGITEDKGRTAVPAGFTFGGGSHEAVIRFPKESGQKPVYVSVTDVLTPAQVKQRQDEEKRLQQEWNDAHPVEVAERNYEQARAELNQANKDVARNQERQAKAVQVYNSRKSELDAANKTLADAKAEIKQFERFAREPMAAGHRMWQMAGLKAQRAQTDVNNKKAAFDAAAKEKSDADVALSSALERRKQKENKEKDAKAKLDKESKRNKPGKATGKGKPVNNKWLNNAGKDLGSPVPDRIANKLRDKEFKSFDDFRKKFWEEVSKDPELSKQFSRNNNDRMKVGKAPKTRTQDVSGKRTSFELHHEKPISQNGGVYDMDNISVVTPKRHIDIHRGK
Physicochemical Analysis
61348.88 Da
9.69
20.70
19.67
0.0359
-0.68
0.86
-0.10
38.32
63.04
0.0556
51450.00
51450.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0224356 VERIFIED: YES
Provenance & Taxonomy
Escherichia coli [Bacterium]
Colicin pyosin nuclease
562
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic
Escherichia coli (Gram-negative)
PMID1603061;10368275 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1603061/
RECORD: Rec_0247759 VERIFIED: YES
Provenance & Taxonomy
Escherichia coli [Bacterium]
Colicin pyosin nuclease
562
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic
Escherichia coli
PMID2045785;1603061;7525540 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2045785/
RECORD: Rec_0342061 VERIFIED: NO
Provenance & Taxonomy
Salmonella enterica subsp. enterica serovar Isangi [Bacterium]
Colicin/Bacteriocin
28901
Structure & Mods
linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic
Escherichia coli (Gram-negative)
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A5W9MHU3/entry