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MYP_055510
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Basic Information
Lan-7
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
7 amino acids
C45H59N9O10
Standard
Sequence
FAYWKAT
Physicochemical Analysis
886.00 Da
8.59
0.76
0.55
0.1083
-0.06
0.11
0.28
-6.24
28.57
0.4286
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
320.19
-0.23
12.0
11.0
24.0
64.0
4.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0098527 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Analogue of TT-232
32630
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
A*=Lanthionine bridge between Alanine
Bio-Activity Profile
Anticancer Cytotoxic
Ovary tumor cell line
16.93±1.84 μM
IC50
PMID9815815 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9815815/
RECORD: Rec_0121873 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Anticancer
PMID9815815 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9815815/
RECORD: Rec_0130133 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Analogue of TT-232
32630
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
A*=Lanthionine bridge between Alanine
Bio-Activity Profile
Anticancer
UMSCC10b
27.69±2.17 μM
IC50
PMID9815815 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9815815/
RECORD: Rec_0219186 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Analogue of TT-232
32630
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
A*=Lanthionine bridge between Alanine
Bio-Activity Profile
Anticancer Cytotoxic
Ovary tumor cell line
17.05±6.61 μM
IC50
PMID9815815 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9815815/
RECORD: Rec_0234748 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Analogue of TT-232
32630
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
A*=Lanthionine bridge between Alanine
Bio-Activity Profile
Anticancer
UMSCC10b
33.88±1.98 μM
IC50
PMID9815815 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9815815/
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