Peptide Database

Peptide NameNL9-4

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC64H87N17O15S

DescriptionStandard

        ACWWAGIRQEF
    

Molecular Weight1366.55 Da

Isoelectric Point (pI)6.04

Net Charge (pH 7.0)-0.21

Net Charge (pH 7.4) -0.42

Charge Density (pH 7.0) -0.0192

GRAVY Index-0.03

Hydrophobic Moment 0.28

Boman Index0.19

Instability Index84.20

Aliphatic Index 53.64

Aromaticity 0.2727

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 528.19

LogP -2.02

H-bond Donors 20.0

H-bond Acceptors 16.0

Rotatable Bonds 40.0

Heavy Atoms 97.0

Ring Count 5.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0415989 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Integrase inhibition

Activity>333 μM

MethodIC50

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