Peptide Database

Peptide NameInterleukin-1 alpha

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length159 amino acids

Chemical FormulaC823H1265N205O243S4

DescriptionStandard

        SAPFSFLSNVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKITVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHPNLFIATKQDYWVCLAGGPPSITDFQILENQA
    

Molecular Weight18047.34 Da

Isoelectric Point (pI)5.30

Net Charge (pH 7.0)-4.27

Net Charge (pH 7.4) -4.69

Charge Density (pH 7.0) -0.0269

GRAVY Index-0.16

Hydrophobic Moment 0.63

Boman Index0.09

Instability Index29.63

Aliphatic Index 90.25

Aromaticity 0.1195

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21430.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7222.82

LogP -63.30

H-bond Donors 244.0

H-bond Acceptors 246.0

Rotatable Bonds 593.0

Heavy Atoms 1275.0

Ring Count 31.0

Amide Bonds 176.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0150526 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyIL-1 family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytokine Growth factor IL-1 family Growth factor signaling Angiogenic