Peptide Database

Peptide NameSLAY-screened peptide P1265

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC95H147N29O33S

DescriptionStandard

        SLLSNAHTSIYQNCRQAFSD
    

Molecular Weight2255.42 Da

Isoelectric Point (pI)6.47

Net Charge (pH 7.0)-0.46

Net Charge (pH 7.4) -0.74

Charge Density (pH 7.0) -0.0230

GRAVY Index-0.47

Hydrophobic Moment 0.51

Boman Index-0.07

Instability Index9.68

Aliphatic Index 68.50

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1037.84

LogP -14.76

H-bond Donors 37.0

H-bond Acceptors 35.0

Rotatable Bonds 73.0

Heavy Atoms 158.0

Ring Count 3.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0253757 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/