Peptide Database

Peptide NameBeta-defensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC463H748N132O136S10

DescriptionStandard

        MRFLRLLLLALGLLLSQLGPGCSPQDTADPTSPYCLTSAHFTELCYLPGQGAGQLTALGQRSDSYICARKGGTCNLSPCPLYNRIEGTCYRGKAKCCIR
    

Molecular Weight10660.34 Da

Isoelectric Point (pI)8.81

Net Charge (pH 7.0)4.50

Net Charge (pH 7.4) 4.08

Charge Density (pH 7.0) 0.0454

GRAVY Index-0.00

Hydrophobic Moment 0.58

Boman Index0.05

Instability Index38.19

Aliphatic Index 85.86

Aromaticity 0.0707

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4266.13

LogP -47.15

H-bond Donors 158.0

H-bond Acceptors 152.0

Rotatable Bonds 343.0

Heavy Atoms 741.0

Ring Count 15.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0351369 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus x Bos taurus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal