Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC116H182N32O27S2

DescriptionStandard

        GIGKFLHSAKKWGKAFVGQIMNC
    

Molecular Weight2521.01 Da

Isoelectric Point (pI)10.04

Net Charge (pH 7.0)3.83

Net Charge (pH 7.4) 3.56

Charge Density (pH 7.0) 0.1667

GRAVY Index0.07

Hydrophobic Moment 0.66

Boman Index0.17

Instability Index-10.96

Aliphatic Index 72.17

Aromaticity 0.1304

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 958.48

LogP -7.07

H-bond Donors 34.0

H-bond Acceptors 34.0

Rotatable Bonds 86.0

Heavy Atoms 177.0

Ring Count 5.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0413225 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus laevis [Animal]

FamilyMagainin

Tax ID8355

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermFluorophore labeling

Other ModsC-term detail: Labelled with Texas Red

Bio-Activity Profile

Function

Cell-penetrating peptide Antimicrobial

TargetHeLa; TM12 cells

MethodFluorescence-based uptake assay

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