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MYP_055373
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Basic Information
H2-2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C107H153N27O20
Standard
Sequence
GLLYFAIFFVAAWHIRGR
Physicochemical Analysis
2137.53 Da
10.84
1.85
1.59
0.1026
1.08
0.26
0.44
42.29
119.44
0.2778
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
746.52
-0.30
28.0
23.0
64.0
154.0
7.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0294848 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antiviral Infection inhibition
Inhibition of post-infection in Huh7.5.1 cells
2.19±0.16 μM
EC50
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperA p7 Ion Channel-derived Peptide Inhibits Hepatitis C Virus Infection in Vitro. | Hong W, Lang Y, Li T, Zeng Z, Song Y, Wu Y, Li W, Cao Z. | J Biol Chem. 2015 Sep 18;290(38):23254-63. | DOI:10.1074/jbc.M115.662452 | PMID:26251517 PMID26251517 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26251517/
RECORD: Rec_0315549 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
Bel7402 cells
~200 μM
CC50
PaperPubMed PMID: 26251517 PMID26251517 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26251517/
RECORD: Rec_0340216 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
cells
83
CC50
PaperPubMed PMID: 26251517 PMID26251517 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26251517/
RECORD: Rec_0379618 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
inhibition of post-infection in Huh7
PaperPubMed PMID: 26251517 PMID26251517 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26251517/
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