Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length200 amino acids

Chemical FormulaC1015H1599N275O267S9

DescriptionStandard

        PKTLPMAHEPMLLLAITEFVANSAAFTYFTAGALRRNISSDMLPRQFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARRQPLLSCRPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLAGTVRLTGLVPNPELALPAPWTPPPALCWAQTLPVPQVKHLETVLKFGLWLFGVPHANSKCCPRPVP
    

Molecular Weight22214.82 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)7.37

Net Charge (pH 7.4) 6.98

Charge Density (pH 7.0) 0.0369

GRAVY Index0.01

Hydrophobic Moment 0.55

Boman Index0.10

Instability Index57.20

Aliphatic Index 93.20

Aromaticity 0.0800

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8450.88

LogP -103.81

H-bond Donors 288.0

H-bond Acceptors 288.0

Rotatable Bonds 686.0

Heavy Atoms 1566.0

Ring Count 51.0

Amide Bonds 215.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0116882 VERIFIED: NO

Provenance & Taxonomy

OrganismMohoua ochrocephala [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria