Peptide Database

Peptide NameType IV secretion protein Rhs

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length2199 amino acids

Chemical FormulaC10279H15954N2936O3377S48

DescriptionStandard

        MNQFIAGSPGSGIATPAGRGWTRRVAALLGFAMLPSLMTPVAFAADVEPLGRPDLEAPRAAKVSPWTVKTNQKLAALGKEIEAANQAAARRGSKDRTRAVDWPGHGSVTLSLSGRDKATPGSLPVTLTEPKTAKDGKQPRAADAVRVEVLDQKTARKLGVKGVVLKVTGPPTGGRARLALDYSAFASAYGGDWAGRLNLLKFPHCLLGDSTKGTCRAPQPLVSVNDRAQGKLSSTLTFKSTAGKAQTMVLAVAAGSQSGAGDYKATPLSSSSSWEAGGSSGTFTWSYPLRTPPAAAGPAPDLSISYDSGAVDGRTANSNNQGTQVGEGFDLTSSYVERQYGSCDDDGQKDKFDRCWKYENASLVLNGKASELVKDDTTKTWRLKNDDASRVIHSWGADNGDDGDANTDPDGDPATDDGKGDGKGEYWTVITGDGTKYVFGLNKLDGAGKDDRTESVWTVPVFGDDSGEPGYSSGSGFSGRDKQQAWRWNLDYVEDTHGNAMSYWYEAERNHYDMLGDDTTGTEYVRGGYLKEIRYGQRKGALFSATPAASNKVVLGYSERCIASGTGCDSLTEDTRDNWPDVPFDAVCKSGDKCTGNTGPSFFTRKRLTGVTTYAWDAAATTPAYAAVDAWSLKHSYPDPGDTGDSADQSLWLKQIEHTGKRGTDLALPPVTFEHTLLPNRVDGQHDNILSFDKPRLRKITSEAGAETVVSYMEADCVYGQAMPKVDDNDKRCYPVYWAPNGEKTPILDWFQKYPVTSVTTSAPHGGKEAVQHTYRYSTPAWHYDDNPFVPEKERTWSLWRGFQRVTHVTGTSGTDQLKTTTVYMQGMNGDRVLGSDNRTPHPDNRKSASVTGISAGAVTDRDQFAGSVRETVTYNGSEEVSGTVNTMWSRKTAVQHKSYADTEAYMVRVADSTERTRVTTTGTAVDRSRTTAYTYDDHGMVSTTEDQGDGAVTGDEKCTRTWYARNADNGINSLVSRTRTVARPCATADSALDLPADSSRPGDVISDAATIYDDATPTAWTASQKPTKGEAVWTGRAKSYGSDGAPAWQKMATTTYDALGRPRTVKNTNDKTVSDTTYIPAGTGPLTSSSATNTKGHKTTTSVAFATGAPVKVIDPNDKITETEYDSLGRVTSVWLPNRSKARKQTANFVYAYNIRNSDLSWVSTGALKGDGTGYNTTYEFYDNLLRLRQVQTPTPVGGRLVSLTLYDSRGLATSAQGDIWDATSAPSGSAVQTEGSQAPIQTDTTYDGAGRATKTVTKTHGVTRWSVDTTYTGDTVTATAPSGGQATAVVTNALGQTTERREYAGPRPTGTDYTTTRYTYTDGGQQETITGPDKAKWSYTYDLFGRQVTATDPDKGTSRTTYDSLDRVDSTFSTEDADKKLLYGYDELNRKTGLWQGEKKDANQLAAWTFDSLYKGQLDTAVRYDGGLTGKAYTRKITKYDPMYQVMESQLLLPKTDELVAAGVPETLSFATGYRPDGTISMASQPAAGGLPSESVEYTYDATGHQLTSRGTSGYLQGATFSPQGDLTQLALGKSGSDTAKKAFLNWEYQPGTRRLTRAYVTDDVHGYMPQELKFTQDDAGNVTSIFDATTQGGTTKPDYQCFAYDGHRRLTESWTPKTADCAASGRTVSNLDGAAPYWTSYTYTEAGQRKTETKHSGTGDSTTSYTYDDTTEAGDKKPHTLDNTAGARAATYDYDVHGNTTSRPGPAAQQSLLWNGEGKLARTTEGSAQTSYLYDADGELLIRRAKGDGDTILYLGGMEVRLTVKGTTKTLSGTRYYTANGQTIAVRTAASGTSGTKLSFLASDHHGTSSLAMDATTYAVTKRYMTPFGASRDLKPGVTWPDDKAFLGKPADAGTGLTHIGAREYDPLTGQFISVDPIIALDQHQSLNGYSYVRNNPASSSDPTGLMDPGGADCGLTGTCNVGSEPKHIKNNPDGVLRGGSGATKKSRGTASTGSSGNTGSGGAAKKSSGCWQFWCQQTPEYELNMGNGSVEMTPEQQAATDAICGVVPIVGTPCDIRDAKRSAEDGDWGGVALSAIAIIPFMDWVKGPRMLEAVKTATKLRNSPGAVTGGYRLPVIAGKWLKGSSGNMGKIPGQVADVLQGREFQTFDDFREAFWKEVSNTPSLAKQFSPANQAVMANGRSPRVVSSQRVGKSDRYVLHHVTPIQHGGGVYDLDNLIVVTPQYHRDVLDRTYHTG
    

Molecular Weight236231.41 Da

Isoelectric Point (pI)6.17

Net Charge (pH 7.0)-13.54

Net Charge (pH 7.4) -16.33

Charge Density (pH 7.0) -0.0062

GRAVY Index-0.63

Hydrophobic Moment 0.77

Boman Index-0.06

Instability Index26.40

Aliphatic Index 58.62

Aromaticity 0.0850

Extinction Coeff. Reduced 396040.00

Extinction Coeff. Oxidized 397290.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0107000 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptomyces sp. JV178 [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal