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MYP_055222
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Basic Information
Glia-gamma30-gliadin (p222–p236)
Immunology ▸ Immunomodulation ▸ Celiac-immunogenic
Venom / Toxin ▸ General toxin ▸ Celiac toxic
Standard
15 amino acids
C70H117N21O22
Standard
Sequence
VQGQGIIQPQQPAQL
Physicochemical Analysis
1604.81 Da
5.50
-0.27
-0.48
-0.0177
-0.41
0.32
0.11
67.87
104.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
711.68
-8.13
20.0
22.0
52.0
113.0
2.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0084794 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
Gliadin
4565
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Celiac-immunogenic
Human gluten-specific T cells / HLA-DQ2
T-cell proliferation assay
PaperThe HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses PMID14530392 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14530392/
RECORD: Rec_0288602 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Celiac toxic
PMID12055577 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12055577/
RECORD: Rec_0360531 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
Gliadin-derived
4565;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Celiac toxic
PaperVader L. W., Kooy Y. M. C., Van Veelen P. A., De Ru A., Harris D., Benckhuijsen, Pena S., Mearin L., Drijfhout J. W., Koning F.. The gluten response in children with celiac disease is directed toward multiple gliadin and glutenin peptides. Gastroententerology, 2002, 122, 1729-1737.