Peptide Database

Peptide NameSLAY-screened peptide P83

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC81H119N17O20S

DescriptionStandard

        PLLHIFNSTAMYIY
    

Molecular Weight1682.98 Da

Isoelectric Point (pI)7.16

Net Charge (pH 7.0)0.04

Net Charge (pH 7.4) -0.07

Charge Density (pH 7.0) 0.0031

GRAVY Index0.76

Hydrophobic Moment 0.32

Boman Index0.47

Instability Index57.59

Aliphatic Index 118.57

Aromaticity 0.2143

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 580.32

LogP -1.56

H-bond Donors 21.0

H-bond Acceptors 22.0

Rotatable Bonds 50.0

Heavy Atoms 119.0

Ring Count 5.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0119826 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/