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MYP_055152
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Basic Information
Somatostatin-14
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Glucagon secretion inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitory neuropeptide
Enzyme modulation ▸ Enzyme inhibition ▸ Insulin secretion inhibition
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Inhibitory neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
14 amino acids
C76H106N18O19S2
Standard
Sequence
AGCKNFFWKTFTSC
Physicochemical Analysis
1639.89 Da
8.91
1.77
1.55
0.1267
0.03
0.32
0.14
30.65
7.14
0.2857
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
613.23
-5.45
24.0
23.0
50.0
115.0
5.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0301511 VERIFIED: YES
Provenance & Taxonomy
Lophius americanus [Animal]
Somatostatin
8073
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-14
Bio-Activity Profile
Hormone Endocrine
Experimental: 1.0±0.2 minutes; /60 seconds; Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Somatostatin-14 (Lophius americanus): PMID 387385##6117506 PMID387385;6117506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/387385/
RECORD: Rec_0310146 VERIFIED: YES
Provenance & Taxonomy
Anguilla anguilla [Animal]
Somatostatin
7936
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-14
Bio-Activity Profile
Hormone Endocrine
Experimental: 1.0±0.2 minutes; /60 seconds; Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Somatostatin 1 (Anguilla anguilla): PMID 2904391##6117506 PMID2904391;6117506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2904391/
RECORD: Rec_0311938 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal] [Animal]; Homo sapiens [Animal] [Animal]; Rattus norvegicus [Animal] [Animal]; Ovis aries [Animal] [Animal]; Canis familiaris [Animal] [Animal]; Bos taurus [Animal] [Animal]; Amia calva [Animal] [Animal]; Torpedo marmorata [Animal] [Animal]; Gadus morhua [Animal]
Somatostatin
9823;9606;10116;9940;9615;9913
Structure & Mods
linear disulfide-stabilized peptide [Linear]
canonical L-amino-acid peptide [L]
3-14
Bio-Activity Profile
Hormone Neuropeptide
RECORD: Rec_0317554 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]; Homo sapiens [Animal]; Mus musculus [Animal]; Rattus norvegicus [Animal]
Somatostatin
9913; 9606; 10090; 10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
3-14
Bio-Activity Profile
Hormonal Endocrine regulation
Cat plasma after intravenous infusion
2.4 min
PaperComparison of the gastric exocrine inhibitory activities and plasma kinetics of somatostatin-28 and somatostatin-14 in cats
RECORD: Rec_0328132 VERIFIED: YES
Provenance & Taxonomy
Pelophylax ridibundus [Animal]
Somatostatin
8406
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-14
Bio-Activity Profile
Hormone Inhibitory neuropeptide
PMID1358069 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1358069/
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