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MYP_055152
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Basic Information
Somatostatin-14
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Glucagon secretion inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitory neuropeptide
Enzyme modulation ▸ Enzyme inhibition ▸ Insulin secretion inhibition
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Inhibitory neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
14 amino acids
C76H106N18O19S2
Standard
Sequence
AGCKNFFWKTFTSC
Physicochemical Analysis
1639.89 Da
8.91
1.77
1.55
0.1267
0.03
0.32
0.14
30.65
7.14
0.2857
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
613.23
-5.45
24.0
23.0
50.0
115.0
5.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0218191 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]; Homo sapiens [Animal]; Mus musculus [Animal]; Rattus norvegicus [Animal]
Somatostatin
9913; 9606; 10090; 10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
3-14
Bio-Activity Profile
Hormonal Endocrine regulation
Rat plasma after intravenous injection
ELISA
7.6 min
PaperA combined in vitro and in vivo study on the interactions between somatostatin and lipid-based liquid crystalline drug carriers and bilayers
RECORD: Rec_0224773 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Somatostatin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-14
Bio-Activity Profile
Hormone Inhibitory neuropeptide
PMID19118555 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19118555/
RECORD: Rec_0228562 VERIFIED: YES
Provenance & Taxonomy
Carassius auratus [Animal]
Somatostatin
7957
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-14
Bio-Activity Profile
Hormone Endocrine
Experimental: 1.0±0.2 minutes; /60 seconds; Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Somatostatin-14 (Carassius auratus): PMID 9827009##6117506 PMID9827009;6117506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9827009/
RECORD: Rec_0234700 VERIFIED: YES
Provenance & Taxonomy
Macaca fascicularis [Animal]
Somatostatin
9541
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-14
Bio-Activity Profile
Hormone Inhibitory neuropeptide
PMID2877919 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2877919/
RECORD: Rec_0237957 VERIFIED: YES
Provenance & Taxonomy
Carassius auratus [Animal]
Somatostatin
7957
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-14
Bio-Activity Profile
Hormone Inhibitory neuropeptide
PMID8575665 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8575665/
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