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MYP_055152
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Basic Information
Somatostatin-14
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Glucagon secretion inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitory neuropeptide
Enzyme modulation ▸ Enzyme inhibition ▸ Insulin secretion inhibition
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Inhibitory neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
14 amino acids
C76H106N18O19S2
Standard
Sequence
AGCKNFFWKTFTSC
Physicochemical Analysis
1639.89 Da
8.91
1.77
1.55
0.1267
0.03
0.32
0.14
30.65
7.14
0.2857
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
613.23
-5.45
24.0
23.0
50.0
115.0
5.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0025242 VERIFIED: YES
Provenance & Taxonomy
Lophius americanus [Animal]
Somatostatin
8073
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-14
Bio-Activity Profile
Hormone Inhibitory neuropeptide
PMID387385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/387385/
RECORD: Rec_0031657 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Somatostatin
9940
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-14
Bio-Activity Profile
Endocrine regulation Neurotransmission modulation Cell proliferation regulation
SS Radioimmunoassay assay
Intravenous infusion in Dog plasma, in vivo; 102 s
PMID6127205 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6127205/
RECORD: Rec_0033039 VERIFIED: YES
Provenance & Taxonomy
Oncorhynchus kisutch [Animal]
Somatostatin
8019
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-14
Bio-Activity Profile
Hormone Inhibitory neuropeptide
PMID2877919 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2877919/
RECORD: Rec_0038013 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide; DSSP H 0.0%, E 0.0%, T 50.0%, C 50.0% [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-14
Bio-Activity Profile
Drug Delivery Vehicle Blood-Brain Barrier
PaperBrainpeps: the blood-brain barrier peptide database PMID22205159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22205159/
RECORD: Rec_0038320 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Somatostatin
9823
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-14
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Reproductive regulator Receptor modulation
Experimental: 1.0±0.2 minutes; /60 seconds; Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Somatostatin-14 (Sus scrofa): PMID 1252409##6117506 PMID1252409;6117506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1252409/
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