Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC299H500N74O87S2

DescriptionStandard

        MSQAVATTVVSIVLTGSTLVSMILGITAILSGGVDAILEIGWSAFVATVKKIVAEREQKAAIAW
    

Molecular Weight6587.74 Da

Isoelectric Point (pI)6.01

Net Charge (pH 7.0)-0.49

Net Charge (pH 7.4) -0.72

Charge Density (pH 7.0) -0.0077

GRAVY Index1.05

Hydrophobic Moment 0.46

Boman Index0.40

Instability Index29.19

Aliphatic Index 135.62

Aromaticity 0.0469

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2546.30

LogP -21.51

H-bond Donors 91.0

H-bond Acceptors 89.0

Rotatable Bonds 219.0

Heavy Atoms 462.0

Ring Count 5.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0139963 VERIFIED: NO

Provenance & Taxonomy

OrganismGeobacillus subterraneus [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

RECORD: Rec_0243117 VERIFIED: NO