Peptide Database

Peptide NameMaximin 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antiviral

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC122H212N32O36

DescriptionStandard

        GIGTKILGGVKTALKGALKELASTYVN
    

Molecular Weight2703.18 Da

Isoelectric Point (pI)9.83

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1021

GRAVY Index0.34

Hydrophobic Moment 0.55

Boman Index0.22

Instability Index-1.74

Aliphatic Index 119.26

Aromaticity 0.0370

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1105.54

LogP -10.85

H-bond Donors 39.0

H-bond Acceptors 39.0

Rotatable Bonds 94.0

Heavy Atoms 190.0

Ring Count 1.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046929 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina maxima [Animal]

Tax ID161274

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans ATCC 2002

Activity3 μM

MethodMIC

RECORD: Rec_0051867 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyMaximin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetStaphylococcus aureus ATCC 2592

Activity19.5 μg/mL

MethodMIC

PaperVariety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification. Eur J Immunol. 2005 Apr;35(4):1220-1229. doi: 10.1002/eji.200425615. PMID: 15770703.; Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima. Peptides. 2002 Mar;23(3):427-435. doi: 10.1016/S0196-9781(01)00641-6. PMID: 11835991. PMID15770703;11835991 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15770703/

RECORD: Rec_0054674 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyMaximin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

PaperVariety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification. Eur J Immunol. 2005 Apr;35(4):1220-1229. doi: 10.1002/eji.200425615. PMID: 15770703.; Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima. Peptides. 2002 Mar;23(3):427-435. doi: 10.1016/S0196-9781(01)00641-6. PMID: 11835991. PMID15770703;11835991 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15770703/

RECORD: Rec_0067420 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyMaximin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetBacillus pyocyaneus CMCCB 10104

Activity19.5 μg/mL

MethodMIC

PaperVariety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification. Eur J Immunol. 2005 Apr;35(4):1220-1229. doi: 10.1002/eji.200425615. PMID: 15770703.; Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima. Peptides. 2002 Mar;23(3):427-435. doi: 10.1016/S0196-9781(01)00641-6. PMID: 11835991. PMID15770703;11835991 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15770703/

RECORD: Rec_0067740 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyMaximin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetCandida albicans ATCC 2002

Activity3 μg/mL

MethodMIC

PaperVariety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification. Eur J Immunol. 2005 Apr;35(4):1220-1229. doi: 10.1002/eji.200425615. PMID: 15770703.; Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima. Peptides. 2002 Mar;23(3):427-435. doi: 10.1016/S0196-9781(01)00641-6. PMID: 11835991. PMID15770703;11835991 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15770703/

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