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MYP_055141
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Basic Information
Beta-defensin 27 (DEFB27; Protein Defb27; rodents, mammals, animals)
Antimicrobial
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
67 amino acids
C348H551N87O94S8
Standard
Sequence
MKTAVLTMVLLLLLSQVIPGSPEKCWKSFGICREECLRKEKFYIFCWDGSLCCVKPKNVPQWSQSSE
Physicochemical Analysis
7714.14 Da
8.60
2.45
2.13
0.0366
0.06
0.41
0.07
66.41
87.16
0.1045
17990.00
18365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2900.53
-21.34
106.0
105.0
255.0
537.0
14.0
70.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0272722 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
10116
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPubMed PMID: 16033865 PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/
RECORD: Rec_0352564 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal
Qualitative functional evidence
PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q32ZG5/entry; https://bblserver.org.in/ampdb/