Peptide Database

Peptide NameBeta-defensin 4B

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC314H522N88O72S7

DescriptionStandard

        MRIRFLLLAFLLVFLLPSPVFPKYISNPVSCLRNGGLCKAACRGHLKKIGTCGISGPKCCRVK
    

Molecular Weight6906.50 Da

Isoelectric Point (pI)10.20

Net Charge (pH 7.0)10.52

Net Charge (pH 7.4) 10.16

Charge Density (pH 7.0) 0.1670

GRAVY Index0.55

Hydrophobic Moment 0.54

Boman Index0.14

Instability Index43.05

Aliphatic Index 109.84

Aromaticity 0.0794

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2525.43

LogP -18.49

H-bond Donors 95.0

H-bond Acceptors 91.0

Rotatable Bonds 226.0

Heavy Atoms 481.0

Ring Count 11.0

Amide Bonds 64.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0018399 VERIFIED: NO

Provenance & Taxonomy

OrganismMarmota monax [Animal]

FamilyDefensin

Tax ID9995

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal