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MYP_055057
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Basic Information
Antimicrobial peptide ISAMP (Ticks, Arthropods, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
46 amino acids
C216H338N74O64S6
Standard
Sequence
PDPGQPWQVKAGRPPCYSIPCRKHDECRVGSCSRCNNGLWGDRTCR
Physicochemical Analysis
5187.84 Da
8.98
3.99
3.79
0.0867
-1.09
0.46
-0.30
30.88
31.74
0.0652
12490.00
12865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2221.29
-28.54
84.0
75.0
161.0
360.0
12.0
49.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0282856 VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
12.3 μg/mL
MIC
PMID12177149;19852941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12177149/
RECORD: Rec_0302874 VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli MG/655
4.2± 0.03 μg/mL
MIC
PMID19852941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19852941/
RECORD: Rec_0309483 VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus cereus
5.8 μg/mL
MIC
PMID12177149;19852941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12177149/
RECORD: Rec_0329530 VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
significant hemolytic activity even up to 150 μg/ml against rabbit red blood cells
150 μg/mL
Hemolysis
PMID12177149;19852941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12177149/
RECORD: Rec_0359266 VERIFIED: NO
Provenance & Taxonomy
Gallus gallus [Animal]; Arthropoda [Animal]
9031; 6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
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