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MYP_055057
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Basic Information
Antimicrobial peptide ISAMP (Ticks, Arthropods, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
46 amino acids
C216H338N74O64S6
Standard
Sequence
PDPGQPWQVKAGRPPCYSIPCRKHDECRVGSCSRCNNGLWGDRTCR
Physicochemical Analysis
5187.84 Da
8.98
3.99
3.79
0.0867
-1.09
0.46
-0.30
30.88
31.74
0.0652
12490.00
12865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2221.29
-28.54
84.0
75.0
161.0
360.0
12.0
49.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0132393 VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus cereus
5.8± 0.05 μg/mL
MIC
PMID19852941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19852941/
RECORD: Rec_0208800 VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
ISAMP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperBiochem Biophys Res Commun. 2009 Dec 18;390(3):511-5 | http://www.ncbi.nlm.nih.gov/pubmed/19852941 PMID19852941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19852941/
RECORD: Rec_0228579 VERIFIED: YES
Provenance & Taxonomy
The black-legged tick [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
10.4 μg/mL
MIC
PaperPurification and characterization of a novel salivary antimicrobial peptide from the tick, Ixodes scapularis
RECORD: Rec_0230955 VERIFIED: YES
Provenance & Taxonomy
The black-legged tick [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus subtilis
12.3 μg/mL
MIC
PaperPurification and characterization of a novel salivary antimicrobial peptide from the tick, Ixodes scapularis
RECORD: Rec_0254325 VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
10.4 μg/mL
MIC
PMID12177149;19852941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12177149/
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