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MYP_055011
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Basic Information
Ranalexin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
20 amino acids
C97H169N23O22S3
Standard
Sequence
FLGGLIKIVPAMICAVTKKC
Physicochemical Analysis
2105.72 Da
9.39
2.74
2.50
0.1369
1.40
0.40
0.43
17.95
136.50
0.0500
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
705.72
-2.42
26.0
28.0
70.0
145.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0103126 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://patents.google.com/patent/US7078380B2/en PatentUS 7078380 B2
RECORD: Rec_0125583 VERIFIED: YES
Provenance & Taxonomy
Rana catesbeiana [Animal]
Ranalexin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
14-20
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Antiparasitic
Pseudomonas aeruginosa
128 μg/mL
MIC
PaperRanalexin, a novel antimicrobial peptide from bullfrog (Rana catesbeiana) skin, structurally related to the bacterial antibiotic, polymyxin
RECORD: Rec_0130978 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0170440 VERIFIED: YES
Provenance & Taxonomy
Aquarana catesbeiana [Animal]
Ranalexin
8400
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
14-20
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
1.9 μM
MIC
PaperD.P. Clark et al. / The Journal of Biological Chemistry 269 (1994) 10849-10855. Ranalexin. A novel antimicrobial peptide from bullfrog (Rana catesbeiana) skin, stucturally related to the bacterial antibiotic, polymyxin Evidence URLhttps://www.uniprot.org/uniprotkb/P39084/entry
RECORD: Rec_0201889 VERIFIED: YES
Provenance & Taxonomy
Rana catesbeiana [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
128 μg/mL
MIC
PMID8144672 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8144672/
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