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MYP_055005
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Basic Information
[G18K]cTI
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C105H166N36O21S4
Standard
Sequence
KWCFRVCYRGICYRRCRK
Physicochemical Analysis
2396.93 Da
10.10
6.72
6.45
0.3731
-0.71
0.65
-0.50
13.04
37.78
0.2222
8480.00
8730.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
975.81
-6.87
43.0
32.0
78.0
166.0
5.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0025807 VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HT-144
3.2±0.1 μM
CC50
PaperPubMed PMID: 31714739 PMID31714739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31714739/
RECORD: Rec_0065824 VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HeLa
6.7±1.1 μM
CC50
PaperPubMed PMID: 31714739 PMID31714739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31714739/
RECORD: Rec_0106302 VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
2.7±0.2 μM
CC50
PaperPubMed PMID: 31714739 PMID31714739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31714739/
RECORD: Rec_0123675 VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
HaCaT
64 μM
CC50
PaperPubMed PMID: 31714739 PMID31714739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31714739/
RECORD: Rec_0157829 VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
1.7±0.1 μM
CC50
PaperPubMed PMID: 31714739 PMID31714739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31714739/
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