Peptide Database

Peptide Name[G1K,L5Y,K8R]cGm

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC97H160N38O24S4

DescriptionStandard

        KCRRYCYRQRCVTYCRGR
    

Molecular Weight2370.81 Da

Isoelectric Point (pI)10.10

Net Charge (pH 7.0)6.72

Net Charge (pH 7.4) 6.45

Charge Density (pH 7.0) 0.3731

GRAVY Index-1.40

Hydrophobic Moment 0.37

Boman Index-0.78

Instability Index24.76

Aliphatic Index 16.11

Aromaticity 0.1667

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1079.45

LogP -12.15

H-bond Donors 47.0

H-bond Acceptors 35.0

Rotatable Bonds 78.0

Heavy Atoms 163.0

Ring Count 3.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0247428 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configstapled cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNo specific N-terminal

C-TermNo specific C-terminal

Disulfide2-15; 6-11

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Anticancer Cytotoxic

TargetK-562

Activity15

MethodCC50

RECORD: Rec_0257375 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configstapled cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNo specific N-terminal

C-TermNo specific C-terminal

Disulfide2-15; 6-11

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Anticancer Cytotoxic

TargetHeLa

Activity15

MethodCC50

RECORD: Rec_0279017 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configstapled cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNo specific N-terminal

C-TermNo specific C-terminal

Disulfide2-15; 6-11

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Anticancer Hemolytic

Targethuman red blood cells

Activity64 μM

Method20.6-32% Hemolysis

RECORD: Rec_0285600 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetKlebsiella pneumoniae ATCC 700603

Activity4-8 μM

MethodMIC

RECORD: Rec_0297173 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configstapled cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNo specific N-terminal

C-TermNo specific C-terminal

Disulfide2-15; 6-11

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Anticancer Cytotoxic

TargetPBMCs

Activity10.4±1.0 μM

MethodCC50

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