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MYP_054976
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Basic Information
Decoralin [AC4]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
11 amino acids
C72H121N15O14
Standard
Sequence
YLLYLIRKLIL
Physicochemical Analysis
1420.82 Da
9.70
1.76
1.55
0.1597
1.55
0.47
0.41
18.88
248.18
0.1818
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
482.70
2.86
18.0
16.0
47.0
101.0
2.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0039068 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
1205Lu
14±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0066270 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0197526 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
A549
29±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0249142 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
HDMEC
256±2 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0269491 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Jurkat
22±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
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