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MYP_054966
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Calpain-1 inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Regulatory peptide ▸ Stimulation activity
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Standard
2 amino acids
C12H24N2O3
Standard
Sequence
IL
Physicochemical Analysis
244.33 Da
5.53
-0.24
-0.44
-0.1200
4.15
0.79
1.22
101.30
390.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
92.42
0.98
3.0
3.0
7.0
17.0
0.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0016794 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Neurotensin
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
PaperCain G. A., Christos T. E., Johnson A. L., Pottorf R. S., Tam S., Schmidt W. K.. Identification of simpler analogs of neurotensin(913) which retain antinociceptive activity. Bioorg. Med. Chem. Lett., 3, 1767-1772, 1993.
RECORD: Rec_0062450 VERIFIED: NO
Provenance & Taxonomy
Gallus gallus [Animal]
90310
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Calpain-1 inhibitory
calpain 1
PaperIn silico investigation of molecular targets, pharmacokinetics, and biological activities of chicken egg ovalbumin protein hydrolysates. Journal of Food Bioactives 17:34-48 (2022).
RECORD: Rec_0101040 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Model sensory peptide
32630
Structure & Mods
linear contiguous peptide sequence [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Bitter
0.67 Rcaf
Relative bitterness (Rcaf)
PaperBitterness of leucine-containing peptides. Agric. Biol. Chem., 51, 2389-2394, 1987
RECORD: Rec_0121653 VERIFIED: YES
Provenance & Taxonomy
unidentified [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Modulator Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
630 μM
IC50
RECORD: Rec_0141726 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
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