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MYP_054952
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Basic Information
Gaegurin peptides SEQID NO: 1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
11 amino acids
C75H106N16O12
Standard
Sequence
FLGWLFKWAKK
Physicochemical Analysis
1423.74 Da
10.30
2.76
2.55
0.2506
0.10
0.55
0.25
4.20
80.00
0.3636
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
463.96
2.31
17.0
15.0
45.0
103.0
6.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0108577 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
25 μg/mL
MIC
PMID21110126 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21110126/
RECORD: Rec_0114240 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
PC-3
47.69 μM
IC50
PaperAnticancer activity of undecapeptide analogues derived from antimicrobial peptide, brevinin-1EMa PMID22644847 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22644847/
RECORD: Rec_0115429 VERIFIED: NO
Provenance & Taxonomy
Glandirana rugosa [Animal]
Gaegurin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
SK-MEL-2
27390 μM
IC50
PaperNovel analogues of antimicrobial and anticancer peptide synthesized and produced from gaegurin 5 Evidence URLhttps://patents.google.com/patent/WO2007133033A1/en PatentWO2007133033A1
RECORD: Rec_0128917 VERIFIED: YES
Provenance & Taxonomy
Korean wrinkled [Animal]; synthetic construct [Synthetic]
Brevinin
33208; 32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID22644847 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22644847/
RECORD: Rec_0131892 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
A-549
25.20 μM
IC50
PaperAnticancer activity of undecapeptide analogues derived from antimicrobial peptide, brevinin-1EMa PMID22644847 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22644847/
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