Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length197 amino acids

Chemical FormulaC910H1500N254O272S12

DescriptionStandard

        MIFPVLAFIVCGLLTRVTKAGWSQPTKCWKNGIGYCRIRCLDNERYMLLCRNKVSCCVPRVLTGEKYPHSRPRPSVALPEDVTLPDNSVFVSPGTRINDEVTFKETPATVKSTSAAGKSTSAAVKPTSAAVKPTSAAGKPTSAPGKSTSAAGKPTSAAVKTTSAAGKSMSVTVKSTYPKTVAIMTTPNPKIATMKTP
    

Molecular Weight20735.96 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)18.51

Net Charge (pH 7.4) 18.10

Charge Density (pH 7.0) 0.0940

GRAVY Index-0.16

Hydrophobic Moment 0.61

Boman Index0.01

Instability Index26.11

Aliphatic Index 68.83

Aromaticity 0.0508

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8340.25

LogP -121.85

H-bond Donors 300.0

H-bond Acceptors 304.0

Rotatable Bonds 663.0

Heavy Atoms 1448.0

Ring Count 32.0

Amide Bonds 203.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013191 VERIFIED: NO

Provenance & Taxonomy

OrganismMesocricetus auratus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10036

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic