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MYP_054932
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Basic Information
Human -defensin-3 (HBD3)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Standard
15 amino acids
C68H131N31O18S3
Standard
Sequence
GKCSTRGRKCCRRKK
Physicochemical Analysis
1767.16 Da
11.02
7.73
7.47
0.5151
-1.89
0.60
-0.97
36.20
0.00
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
862.86
-12.82
37.0
29.0
66.0
120.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0094781 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Enterococcus faecalis
PMID28956355 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28956355/
RECORD: Rec_0301365 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
Human dental pulp-derived cells stimulated with Streptococcus gordonii lipoprotein
50 μg/mL
PaperSynthetic Human β Defensin-3-C15 Peptide in Endodontics: Potential Therapeutic Agent in Streptococcus gordonii Lipoprotein-Stimulated Human Dental Pulp-Derived Cells. PMID31861863 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31861863/ PatentEP3111951B1
RECORD: Rec_0380432 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Candida albicans
PMID28956355 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28956355/
RECORD: Rec_0410241 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Streptococcus mutans
PMID28956355 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28956355/