Peptide Database

Peptide NameCecropin 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC196H317N59O57

DescriptionStandard

        GWLRDFGKKIERVGQHTRDATLQVIDIAQKAANVAETFK
    

Molecular Weight4411.97 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)1.85

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.0475

GRAVY Index-0.51

Hydrophobic Moment 0.94

Boman Index-0.11

Instability Index27.62

Aliphatic Index 85.13

Aromaticity 0.0769

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1922.92

LogP -18.54

H-bond Donors 67.0

H-bond Acceptors 60.0

Rotatable Bonds 152.0

Heavy Atoms 312.0

Ring Count 5.0

Amide Bonds 42.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0357936 VERIFIED: YES

Provenance & Taxonomy

OrganismMusca domestica [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)