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MYP_054907
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Basic Information
human MUC7 20-Mer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Standard
20 amino acids
C112H186N38O24S2
Standard
Sequence
LAHQKPFIRKSYKCLHKRCR
Physicochemical Analysis
2513.05 Da
10.57
6.91
6.57
0.3455
-1.05
0.74
-0.46
48.88
63.50
0.1000
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1038.12
-8.18
40.0
35.0
86.0
176.0
5.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0032802 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa
4.41 μM
EC50
PaperPubMed PMID: 12543672 PMID12543672 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12543672/
RECORD: Rec_0046248 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida glabrata
PMID12543672 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12543672/
RECORD: Rec_0048542 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans (DIS)
5.85 μM
EC50
PaperPubMed PMID: 12543672 PMID12543672 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12543672/
RECORD: Rec_0048751 VERIFIED: YES
Provenance & Taxonomy
Gorilla gorilla [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0078120 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli
1.61 μM
ED50
PaperMUC7 20-Mer: Investigation of Antimicrobial Activity, Secondary Structure, and Possible Mechanism of Antifungal Action.
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