Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length441 amino acids

Chemical FormulaC2179H3453N589O610S11

DescriptionStandard

        VYPGFVVRITQAGLDYARQHGVAILEQELHQLRLPDISGDFRVRRVGKVHYELSSLNLRSFRLPSSQISPIPNVGLQVSISDAFAVVDGNWRVKLHFIRDHGSFDLKVEDLSIRINLKLGSDGSGKPTADVSDCSAHVSSVRVHFSGKFSWLYNLFHSAVESVFRRTLESKVCEQVVSSVRGELQSYLRTLPVTAKIDAVAGIDYSLVAPPAAIAQALDADLKGEFFSLAHRSAVPFSPPPLAIPPDQARMVYFGASSYFFNTASLVYHAAGALVFELTDSMIPKGLDFHLNTSTFSAFVPQLEKMYPDMLMKLRLSTPAAPFLSIGPEGLSLQPVVDIQAYAILPSASLAPLFLLNLVSGARLVVPAAAAALGACELLAMSLLTRSPCPVHPQVRTLQSVMNILASSILLPRLNARLAQGFPLPLLRRTQLSNVLVQSHQ
    

Molecular Weight48014.02 Da

Isoelectric Point (pI)8.99

Net Charge (pH 7.0)5.86

Net Charge (pH 7.4) 4.87

Charge Density (pH 7.0) 0.0133

GRAVY Index0.25

Hydrophobic Moment 0.70

Boman Index0.15

Instability Index46.83

Aliphatic Index 107.69

Aromaticity 0.0816

Extinction Coeff. Reduced 27390.00

Extinction Coeff. Oxidized 27640.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0103411 VERIFIED: NO

Provenance & Taxonomy

OrganismNothocercus julius [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria