Peptide Database

Peptide NameSperm-associated antigen 11B (Human epididymis-specific protein 2) (He2) (Protein EP2) (Sperm antigen HE2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length103 amino acids

Chemical FormulaC503H810N162O138S3

DescriptionStandard

        MRQRLLPSVTSLLLVALLFPGSSQARHVNHSATEALGELRERAPGQGTNGFQLLRHAVKRDLLPPRTPPYQVHISHREARGPSFRICVDFLGPRWARGCSTGN
    

Molecular Weight11431.01 Da

Isoelectric Point (pI)11.49

Net Charge (pH 7.0)7.93

Net Charge (pH 7.4) 7.42

Charge Density (pH 7.0) 0.0770

GRAVY Index-0.36

Hydrophobic Moment 0.65

Boman Index-0.08

Instability Index36.63

Aliphatic Index 85.24

Aromaticity 0.0583

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4794.06

LogP -52.24

H-bond Donors 171.0

H-bond Acceptors 154.0

Rotatable Bonds 367.0

Heavy Atoms 806.0

Ring Count 21.0

Amide Bonds 110.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0173196 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilySPAG11

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)