Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC390H609N109O105S9

DescriptionStandard

        MALIRKTFYFVFAVFFILVQQPSGCQAGLEFSEPFPSGRFAVCESCKLGRGKCRKECLENEKPDGSCRLNFLCCRQR
    

Molecular Weight8793.26 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)4.43

Net Charge (pH 7.4) 4.08

Charge Density (pH 7.0) 0.0576

GRAVY Index-0.06

Hydrophobic Moment 0.46

Boman Index-0.03

Instability Index53.30

Aliphatic Index 65.84

Aromaticity 0.1299

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3464.41

LogP -32.19

H-bond Donors 128.0

H-bond Acceptors 119.0

Rotatable Bonds 292.0

Heavy Atoms 613.0

Ring Count 14.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0128153 VERIFIED: NO

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0275913 VERIFIED: NO