Peptide Database

Peptide NameCyclotide vaby E

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC126H192N36O42S6

DescriptionStandard

        GLPVCGETCFGGTCNTPGCSCDPWPVCTRN
    

Molecular Weight3075.48 Da

Isoelectric Point (pI)4.37

Net Charge (pH 7.0)-1.30

Net Charge (pH 7.4) -1.59

Charge Density (pH 7.0) -0.0432

GRAVY Index-0.05

Hydrophobic Moment 0.31

Boman Index0.12

Instability Index56.17

Aliphatic Index 32.33

Aromaticity 0.0667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1211.68

LogP -17.59

H-bond Donors 46.0

H-bond Acceptors 47.0

Rotatable Bonds 87.0

Heavy Atoms 210.0

Ring Count 7.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0023689 VERIFIED: NO

Provenance & Taxonomy

OrganismViola tricolor [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0059844 VERIFIED: YES

Provenance & Taxonomy

OrganismViola abyssinica [Plant],Viola tricolor [Plant]

FamilyCyclotide

Tax ID214053

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial Cytotoxic