Peptide Database

Peptide NameAstexin-3 (Class II lasso peptide) (Ribosomally synthesized and post-translationally modified peptide) (RiPP)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length49 amino acids

Chemical FormulaC231H366N68O72S2

DescriptionStandard

        MRTYNRSLPARAGLTDLGKVTTHTKGPTPMVGLDSVSGQYWDQHAPLAD
    

Molecular Weight5311.92 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)0.68

Net Charge (pH 7.4) 0.35

Charge Density (pH 7.0) 0.0138

GRAVY Index-0.57

Hydrophobic Moment 0.50

Boman Index-0.04

Instability Index15.82

Aliphatic Index 65.71

Aromaticity 0.0612

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2236.85

LogP -26.20

H-bond Donors 78.0

H-bond Acceptors 77.0

Rotatable Bonds 167.0

Heavy Atoms 373.0

Ring Count 10.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417522 VERIFIED: YES

Provenance & Taxonomy

OrganismAsticcacaulis excentricus [Bacterium]

Tax ID573065

Structure & Mods

Configlasso peptide topology [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Non-hemolytic