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MYP_054827
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Basic Information
Pb-CATH4 bivittatus antimicrobial peptides peptide derivative
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C143H226N54O29
Standard
Sequence
TRSRWRRFIRGAGRFARRYGWRIAL
Physicochemical Analysis
3165.67 Da
12.00
8.40
8.21
0.3359
-0.90
1.07
-0.46
95.35
58.80
0.2000
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1411.09
-12.25
58.0
38.0
103.0
226.0
7.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0196763 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00530-17. doi: 10.1128/AAC.00530-17. PMID: 28630199. PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
RECORD: Rec_0238510 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Clinical isolates:Escherichia coli
4.7 μg/mL
MIC
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00530-17. doi: 10.1128/AAC.00530-17. PMID: 28630199. PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
RECORD: Rec_0245560 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli (ATCC 25922)
1 μg/mL
MIC
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00530-17. doi: 10.1128/AAC.00530-17. PMID: 28630199. PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
RECORD: Rec_0257729 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00530-17. doi: 10.1128/AAC.00530-17. PMID: 28630199. PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
RECORD: Rec_0374458 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
1.18 μg/mL
MIC
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00530-17. doi: 10.1128/AAC.00530-17. PMID: 28630199. PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
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