Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length725 amino acids

Chemical FormulaC3410H5327N925O1062S18

DescriptionStandard

        MSIMLYIHPPHGCYAFKMEINMSDNETVPTEGVDYGHTIVGWPVRPKWGQPDAGASIGINPDFDPVTGNGWLPEEDGYHHDLPAGTPADVQSAINQVKQAGGLMSVDLRKLRPAAGYPWDPTVAWDPVFVYFPAKAVSDSNLSAGSLPETVPAHSRIQDDVHDGAQFISVTGSGSQPYNLPVIKATPTPRGPYYTIGHLPGPMGPYTFTFNANAPHSEMHFARDEEKVSALHPAGFTVGANTTDCIVVFPEGSGLEPLYFSMTVILPEGPLKQRQEEENQARAKADAEAKAKAEAEAKAKAEAEAKAKAEREALFARAGVVPAPTYTPEMVKAAEAALGTAGVMVLGQTPGAMQLSVAGGGVLTATGEVLSSLGAAVGRAIASLGATATAGTAGPMVAAASAILFPPVAGEGSDRVPGRDLNAMFALNAQLLAGQDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPPPATPSDTASPPPSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGVEPVYVMLSGLYGETNAKGKYSGRDYNSDKAGGPIQDLDWKTATIDREGVDKVKLHTGRFGELPDNKVMIDRLENILKGELQATDTDLRFYTHEIRELERYRNLGIKDGVIPDNYDEVWNNTHTATLEDYKINEKTQPLYTPEAEEAYRKAEEGK
    

Molecular Weight76850.51 Da

Isoelectric Point (pI)4.95

Net Charge (pH 7.0)-30.00

Net Charge (pH 7.4) -31.24

Charge Density (pH 7.0) -0.0414

GRAVY Index-0.28

Hydrophobic Moment 0.77

Boman Index0.07

Instability Index34.63

Aliphatic Index 78.12

Aromaticity 0.0662

Extinction Coeff. Reduced 78270.00

Extinction Coeff. Oxidized 78395.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0083066 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella houtenae [Bacterium]

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli