Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2315H3630N616O654S11

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGIAILEKELTQLKLPDISGDSRVLHVGKVHYELSRLSLRNFQLPYSRITPIANVGLQVSISNAFAELYGDWRVKFLFIRDRGSFDLKVENAYIKISLRLGSDTTGKPTISTSDCSTRISKVRVRFSGKLGWLYNLFHRVIEARFRKILEDKVCSSVAESVHNELQTYVQTLPVTATIDAMTGIDYALVAPPNATAQSLDADLKGEFYSLAHRSTVPFSPLPLAFPSDHDRMVYFGASSYFFNTASFAYHEAGALVFEITNDMISKEAEFSLNTSTFSAFIPQLEEMYPNMPMKFKLFTPTAPFLNIGPERISLRPVVDAQAYAILPNSSVAPLFLLSLVRNVSAVINVRSGRIVGSLDVGRIRLSLKDSAVGTFQVRMMQSLMNVFASSILLPKLNARLDEGFPLPLPDRIQLFNTLVRFHQNFLLLGADVHFQPQ
    

Molecular Weight50908.03 Da

Isoelectric Point (pI)9.02

Net Charge (pH 7.0)5.29

Net Charge (pH 7.4) 4.48

Charge Density (pH 7.0) 0.0116

GRAVY Index0.07

Hydrophobic Moment 0.67

Boman Index0.10

Instability Index31.98

Aliphatic Index 99.21

Aromaticity 0.1031

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0203593 VERIFIED: NO

Provenance & Taxonomy

OrganismPtilonorhynchus violaceus (Satin bowerbird) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria