Peptide Database

Peptide NameFP4

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-Influenza A virus

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC117H166N28O18

DescriptionStandard

        RRKKWLVFFVIFYFFR
    

Molecular Weight2252.75 Da

Isoelectric Point (pI)11.73

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.2973

GRAVY Index0.45

Hydrophobic Moment 0.37

Boman Index0.06

Instability Index73.26

Aliphatic Index 85.00

Aromaticity 0.4375

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 773.58

LogP 2.01

H-bond Donors 30.0

H-bond Acceptors 23.0

Rotatable Bonds 71.0

Heavy Atoms 163.0

Ring Count 8.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0387186 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Anti-Influenza A virus Fusion inhibition

TargetInfluenza A virus PR8/Viet (H5N1) | MDCK cells

Activity0.1325 μM

MethodIC50

Half-LifeMammalian: 1 h; Yeast: 2 min; E. coli: 2 min

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